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The effects of adipose tissue and adipocytokines in human pregnancy

文献类型: 会议论文

第一作者: G. Valsamakis

作者: G. Valsamakis 1 ; S. Kumar 2 ; G. Creatsas 1 ; G. Mastorakos 1 ;

作者机构: 1.Endocrine Unit, 2nd Department of Obstetrics and Gynaecology, Aretaieion University Hospital, Athens Medical School, Athens, Greece

2.Warwickshire Institute for the Study of Diabetes, Endocrinology and Metabolism (WISDEM), University Hospital Coventry and Warwick Medical School, Coventry, United Kingdom

关键词: adipose tissue;adipocytokines;pregnancy

会议名称: Athens Congress on Women's Health and Disease

主办单位:

页码: 76-81

摘要: During pregnancy, important changes take place in maternal metabolism because of the growing fetus and placental formation. The increase in insulin resistance during pregnancy is paralleled by the progressive increase of maternal adipose tissue deposition. This review examines the topography of fat mass deposition during pregnancy in relation to factors such as parity and maternal age that might affect this deposition. We also examine adipose tissue markers, such as pregravid weight and weight gain during pregnancy, and their effect on fetal growth and pregnancy outcomes. In addition, this review studies the possible effects of cytokines that are produced by adipose tissue and the placenta on maternal metabolism and its complications. Finally, we also consider the possible role of maternal adipocytokines and fetal adipocytokines on fetal growth.

分类号: R173-532

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