文献类型： 外文期刊
作者： Cao, Liang 1 ; Li, Bin 1 ; Shehla, Nuzhat 1 ; Gong, Li-min 1 ; Jian, Yu-Qing 1 ; Peng, Cai-Yun 1 ; Sheng, Wen-Bing 1 ; Li 1 ;
作者机构： 1.Hunan Univ Chinese Med, Sch Pharm, Innovat Mat Med Res Inst, TCM & Ethnomed Innovat & Dev Int Lab,Acad Attaur, Changsha 410208, Peoples R China
2.Hunan Acad Agr Sci, Inst Agr Environm & Agroecol, Changsha 410125, Peoples R China
3.Univ Karachi, Int Ctr Chem & Biol Sci, HEJ Res Inst Chem, Karachi 75270, Pakistan
4.First Peoples Hosp Huaihua, Clin Expt Res Ctr, Huihua 418000, Peoples R China
关键词： Kadsura heteroclita; Schisandraceae; Xuetong; Tujia ethnomedicine; Triterpenoids
期刊名称：FITOTERAPIA （ 影响因子：2.882； 五年影响因子：3.202 ）
ISSN： 0367-326X
年卷期： 2020 年 140 卷
页码：
收录情况： SCI
摘要： In the present work, we reported the triterpenoids isolated from n-butanol fraction of Kadsura heteroclita which is a Tujia ethnomedicine with trivial name "Xuetong". This effort resulted in the isolation of six unpresented triterpenoids xuetongsu A-F (1-6), along with five known triterpenoids (7-11). The structures of the reported compounds were established on the 1D, and 2D NMR and HRESIMS spectra, along with CD spectroscopic analysis. Moreover, the absolute stereochemistry of compound 7 was determined by X-ray diffraction analysis. Antioxidant and cytotoxic activities were evaluated for all isolated compounds, compound 7 shown weak cytotoxic activity against HL-60 with IC50 value of 50.0 mu M.
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