The effects of Chuanxiong on the pharmacokinetics of warfarin in rats after biliary drainage
文献类型： 外文期刊
作者： Li, Haigang 2 ; Zhang, Chunhu 1 ; Fan, Rong 1 ; Sun, Hua 3 ; Xie, Haitang 4 ; Luo, Jiekun 1 ; Wang, Yang 1 ; Lv, Huiying; 1 ;
作者机构： 1.Cent S Univ, Xiangya Hosp, Lab Ethnopharmacol, Dept Integrated Tradit Chinese & Western Med, Changsha 410008, Hunan, Peoples R China
2.Changsha Med Univ, Dept Pharm, Changsha 410219, Hunan, Peoples R China
3.Wannan Med Coll, Yijishan Hosp, Anhui Prov Ctr Drug Clin Evaluat, Wuhu 241001, Peoples R China
4.Wannan Med Coll, Yijishan Hosp, Anhui Prov Ctr Drug
关键词： Warfarin;Chuanxiong;Pharmacokinetics;Enterohepatic circulation;LC-MS/MS;Biliary drainage
期刊名称：JOURNAL OF ETHNOPHARMACOLOGY （ 影响因子：4.36； 五年影响因子：4.488 ）
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收录情况： SCI
摘要： Ethnopharmacological relevance: Chuanxiong Rhizoma (rhizomes of Ligusticum chuanxiong Hort), known as Chuanxiong in Chinese, has been used for treating cardiovascular diseases for centuries. Chuanxiong is a classical activating blood circulation herb in the treatment of thromboembolism heart diseases. Warfarin often combines with herbal prescriptions containing Chuanxiong in China.
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