文献类型: 外文期刊
作者: Dong, Zheng 1 ; Guo, Liang 1 ; Li, Xiaoxiang 1 ; Li, Yongchao 1 ; Liu, Wenqiang 1 ; Chen, Zuwu 1 ; Liu, Licheng 1 ; Liu, Zhixi 1 ; Guo, Yujing 1 ; Pan, Xiaowu 1 ;
作者机构: 1.Hunan Acad Agr Sci, Hunan Rice Res Inst, Changsha 410125, Peoples R China
2.Minist Agr, Key Lab Indica Rice Genet & Breeding Middle & Lowe, Changsha 410125, Peoples R China
关键词: arsenic; GWAS; MYB transcription factor; polished rice
期刊名称:GENES ( 影响因子:3.5; 五年影响因子:3.9 )
ISSN:
年卷期: 2023 年 14 卷 12 期
页码:
收录情况: SCI
摘要: The accumulation of arsenic (As) in rice poses a significant threat to food safety and human health. Breeding rice varieties with low As accumulation is an effective strategy for mitigating the health risks associated with arsenic-contaminated rice. However, the genetic mechanisms underlying As accumulation in rice grains remain incompletely understood. We evaluated the As accumulation capacity of 313 diverse rice accessions grown in As-contaminated soils with varying As concentrations. Six rice lines with low As accumulation were identified. Additionally, a genome-wide association studies (GWAS) analysis identified 5 QTLs significantly associated with As accumulation, with qAs4 being detected in both of the experimental years. Expression analysis demonstrated that the expression of LOC_Os04g50680, which encodes an MYB transcription factor, was up-regulated in the low-As-accumulation accessions compared to the high-As-accumulation accessions after As treatment. Therefore, LOC_Os04g50680 was selected as a candidate gene for qAs4. These findings provide insights for exploiting new functional genes associated with As accumulation and facilitating the development of low-As-accumulation rice varieties through marker-assisted breeding.
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