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Oligomeric Proanthocyanidins: An Updated Review of Their Natural Sources, Synthesis, and Potentials

文献类型： 外文期刊

作者： Nie, Fanxuan 1 ; Liu, Lili 1 ; Cui, Jiamin 1 ; Zhao, Yuquan 1 ; Zhang, Dawei 1 ; Zhou, Dinggang 1 ; Wu, Jinfeng 1 ; Li, Bao 3 ; Wang, Tonghua 3 ; Li, Mei 3 ; Yan, Mingli 2 ;

作者机构： 1.Hunan Univ Sci & Technol, Sch Life & Hlth Sci, Xiangtan 411201, Peoples R China

2.Hunan Univ Sci & Technol, Hunan Key Lab Econ Crops Genet Improvement & Integ, Xiangtan 411201, Peoples R China

3.Hunan Acad Agr Sci, Crop Res Inst, Changsha 410125, Peoples R China

4.Hunan Acad Agr Sci, Hunan Engn & Technol Res Ctr Hybrid Rapeseed, Changsha 410125, Peoples R China

关键词： oligomeric proanthocyanidins; antioxidant; molecular structure; natural source; cardiovascular disease; diabetes mellitus

期刊名称：ANTIOXIDANTS （ 影响因子：7.0； 五年影响因子：7.3 ）

ISSN：

年卷期： 2023 年 12 卷 5 期

页码：

收录情况： SCI

摘要： Oligomeric Proanthocyanidins (OPCs), as a class of compounds widely found in plants, are particularly abundant in grapes and blueberries. It is a polymer comprising many different monomers, such as catechins and epicatechins. The monomers are usually linked to each other by two types of links, A-linkages (C-O-C) and B-linkages (C-C), to form the polymers. Numerous studies have shown that compared to high polymeric procyanidins, OPCs exhibit antioxidant properties due to the presence of multiple hydroxyl groups. This review describes the molecular structure and natural source of OPCs, their general synthesis pathway in plants, their antioxidant capacity, and potential applications, especially the anti-inflammatory, anti-aging, cardiovascular disease prevention, and antineoplastic functions. Currently, OPCs have attracted much attention, being non-toxic and natural antioxidants of plant origin that scavenge free radicals from the human body. This review would provide some references for further research on the biological functions of OPCs and their application in various fields.

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